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Having described the formulation of the pharmaceutical composition, the reduced dosages of CNS active agents as part of the pharmaceutical composition of the present invention, are set forth below.

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Alternatively, for administration by inhalation or insufflation, the compounds according to the invention may take the form of a dry powder composition, for example a powder mix of the compound and a suitable powder base such as lactose or starch.

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In a further embodiment, two different CNS agents are incorporated into the kit, one is used in conjunction with neuromodulators in a single or separate form and the second has a different therapeutic mode of action which may be synergistic or complementary to the first CNS agent.

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