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May reduce natriuretic effect of furosemide and thiazide diuretics; observe closely for signs of renal failure and diuretic efficacy.
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Ketorolac is widely used intramuscularly and intravenously for moderately severe acute pain: there have been more than 500 million injections in the United States since its introduction, and nearly 40 million injections in 2010 alone.
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Non-steroidal anti-inflammatory drug-related hepatic damage in France and Spain: analysis from national spontaneous reporting systems.
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NSAIAs) or nonsteroidal anti-inflammatory medicines ( NSAIMs), are a that groups together that provide (pain-killing) and (fever-reducing) effects, and, in higher doses, effects.
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Smith of Kansas State University in Manhattan and her colleagues studied possible indicators of pain in cats that they had spayed and then treated with varying amounts of analgesics, they report in the November American Journal of Veterinary Research.
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The major drawback of these medications is that they also block the beneficial effects of the prostaglandins: the decrease in the tissue inflammatory response to surgical trauma and the concomitant reduction in peripheral nociception and pain perception.
Tear osmolarity is the best single diagnostic test for dry eye.
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The pharmacological activity of Ketorolac tromethamine in reducing inflammation may diminish the utility of this diagnostic sign in detecting complications of presumed noninfectious, painful conditions.
Placing a rag soaked in pure castor oil on your stomach, directly over your gallbladder, is said to help reduce pain associated with the gallbladder quickly and dramatically.
The deleterious gastrointestinal effects of tNSAIDs are cause for concern because of their frequency and seriousness.
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The nurse is assessing a multigravida, 36 weeks gestation for symptoms of pregnancy-induced hypertension and preeclampsia.
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One anecdotal example from the practice of one of the editors is that of a 65-year-old man with a 5-year history of more than 60 stones.
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Linear Kinetics: In adults, following administration of single ORAL, IM or IV doses of TORADOL in the recommended dosage ranges, the clearance of the racemate does not change.
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Sixty-two percent (62%) of reportedly therapeutic overdoses were of more than 24 grams of acetaminophen; the authors reported that the acetaminophen dose was staggered over a number of hours or days.
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Additionally, the evidence does not support the notion that IM ketorolac is more effective than oral NSAIDs for pain relief in patients with acute renal colic.
The retracted studies were not submitted to either the FDA or the European Union's regulatory agencies prior to the drug's approval.
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Undertreatment of acute pain is suboptimal medical treatment, and patients receiving long-term OAT are at particular risk.
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Other NSAID hypersensitivity reactions are allergy-like symptoms but do not involve true allergic mechanisms; rather, they appear due to the ability of NSAIDs to alter the metabolism of arachidonic acid in favor of forming metabolites that promote allergic symptoms.
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Oral formulation is used as continuation therapy in adults; total combined duration of parenteral and oral therapy in adults should not exceed 5 days because of increased risk of serious adverse effects.
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