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T2DM patients followed up for 14 years, indicated that both postprandial blood glucose and HbA1c predict cardiovascular events and all-cause mortality, showing the independent predictive power of postprandial glycemia on cardiovascular events after correction for HbA1c.
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Conduct baseline hepatic panel and creatine kinase (CK) before initiating treatment.
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Fenofibrate treatment significantly reduced apo B from baseline to endpoint as compared with placebo (-25.
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The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study (Current Controlled Trials number, ISRCTN64783481) of participants with type 2 diabetes showed a beneficial effect of fenofibrate (at a dose of 200 mg per day) on the progression of diabetic retinopathy.
Individuals who took high doses of an omega-3 fatty acid with the statin were 19 percent less likely to have major coronary events (i.
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Every six months for the first half of the study, and then annually, blood for lipid analysis was drawn while patients were fasting and was processed according to a standardized protocol.
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Creatine phosphokinase (CPK) levels should be assessed in patients reporting these symptoms, and fenofibrate therapy should be discontinued if markedly elevated CPK levels occur or myopathy is diagnosed.
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The Task Force on diabetes, pré-diabetes and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collaboration with the European Association for the Study of Diabetes (EASD).
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Figure 3 Subgroup Effects in the ACCORD Blood-Pressure Trial.
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