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Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by clarithromycin extended-release tablets or other antibacterial drugs in the future.

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Tonsillitis due to Streptococcus pyogenes (The usual drug of choice in the treatment and prevention of streptococcal infections and the prophylaxis of rheumatic fever is penicillin administered by either the intramuscular or the oral route.

Unlike the 80 to 90% response to long-term erythromycin therapy reported for DPB, pulmonary function, total cell counts, and neutrophil percentages in bronchoalveolar lavage fluid did not improve in these patients ().

Enhancement of the in vitro and in vivo activities of clarithromycin against Haemophilus influenzae by 14-hydroxy-clarithromycin, its major metabolite in humans.

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The recommended adult dose is 500 mg clarithromycin given twice daily (q 12 h) or three times daily (q 8 h) and 400 mg ranitidine bismuth citrate given twice daily (q 12 h) for 14 days.

The combination of clarithromycin and omeprazole was as effective as omeprazole alone for healing duodenal ulcer.

There have been reports of individuals with a history of penicillin hypersensitivity who have experienced severe reactions when treated with cephalosporins.

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May interact with drugs metabolized by CYP450 enzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A).

In contrast to TB, basic information, such as the efficacy of many individual agents in the treatment of NTM disease, is not available.

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When Clarithromycin and terfenadine were coadministered, plasma concentrations of the active acid metabolite of terfenadine were threefold higher, on average, than the values observed when terfenadine was administered alone.

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The agar-based media may also be used for susceptibility testing.

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Patients with other respiratory conditions (active thoracic malignancy, asthma, and interstitial lung disease), those already on long term macrolide treatment, and those treated with primary palliative intent were excluded.

Avoid any instances that can lead to taking this drug in large amount as this can result to severe side effects.

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Clarithromycin exposure was decreased by etravirine; however, concentrations of the active metabolite, 14-OH-clarithromycin, were increased.

New site of modification of 23S rRNA associated with clarithromycin resistance of Helicobacter pylori clinical isolates.

Stop using this medicine and check with your doctor right away if you or your child have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin.

Treatment recommendations for NTM lymphadenitis are outlined in discussions of individual NTM species.

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Budesonide is in a class of medications called corticosteroids.

Therefore, for patients who fail therapy, Clarithromycin susceptibility testing should be done, if possible.

Biaxin should not be used in children younger 6 months; safety and effectiveness in these children have not been confirmed.

Additionally, if patients dropped out of the study due to an adverse event related to the study drug, they were included in the analysis as failures of therapy.

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